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Article

The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases

31 Mar 2016

Abstract excerpt

Nucleotide signaling molecules contribute to the regulation of cellular pathways. In the immune system, cyclic adenosine monophosphate (cAMP) is well established as a potent regulator of innate and adaptive immune cell functions. Therapeutic strategies to interrupt or enhance cAMP generation or effects have immunoregulatory potential in autoimmune and inflammatory disorders. Here, we provide an overview of the...

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PMID: 27065076
DOI: 10.3389/fimmu.2016.00123

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