Article
Sequence variations of the hypervariable region of hepatitis C virus and their clinical significance.
Chinese medical journal - 1 Dec 2000
Zhang S, Wang W, Zhou K, Liu H
Abstract excerpt
OBJECTIVE: To understand the clinical significance of sequence variations in the hypervariable region (HVR) of hepatitis C virus during infection. METHODS: Eight patients with acute hepatitis C and 20 patients with chronic hepatitis C were followed up for two years. Blood samples were taken at intervals of six months for analysis of HCV-HVR sequences by reverse transcription-polymerase chain reaction (RT-PCR) and...
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