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Article

Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection.

Hepatology (Baltimore, Md.) - 1 Dec 1993

Kurosaki M, Enomoto N, Marumo F, Sato C

Abstract excerpt

To evaluate the clinical significance of sequence variations in the hypervariable region of hepatitis C virus during the course of chronic infection, we performed pairwise comparison of the predominant nucleotide sequences. Hepatitis C virus RNA was extracted from two plasma samples obtained from 12 chronically infected Japanese patients over approximately 1 yr. Complementary DNA containing the hypervariable...

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PMID: 8244252

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