Article
Genetic characterization of hypervariable region 1 in patients chronically infected with hepatitis C virus genotype 2.
Journal of medical virology - 1 Jul 2001
Fan X, Di Bisceglie A M
Abstract excerpt
The hypervariable region 1 (HVR1) has been most reliably identified in the genome of HCV genotype 1 isolates and thought to possibly play a role in immune evasion and development of chronic infection. There are few studies, however, of other HCV genotypes to determine if they also have such a hypervariable region present, and it is unclear whether or not there is any genotype-dependent difference in the genetic...
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