Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus.

Biochemical and biophysical research communications - 30 Nov 1992

Kato N, Ootsuyama Y, Ohkoshi S, Nakazawa T, Sekiya H, Hijikata M, Shimotohno K

Abstract excerpt

We previously identified two hypervariable regions [HVR1 (27 amino acids) and HVR2 (7 amino acids)] in the putative envelope glycoprotein (gp70) by comparison of the amino acid sequences of many isolates of the HCV-II genotype. To understand the functional features of these HVRs, using the polymerase chain reaction we analyzed the rate of actual sequence variability in the region including HVR1 and HVR2 of HCV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genotype

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Restriction Mapping

Share to RNA, Viral

Source

Identifiers

PMID: 1333186
DOI: 10.1016/0006-291x(92)91533-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus.PMID 1333186Read ↗

[Sequence diversity and variability in the putative envelope proteins including hypervariable regions of hepatitis C virus].Semantic proximity Read ↗

Characterization of hypervariable region in hepatitis C virus envelope protein during acute and chronic infection.Semantic proximity Read ↗

Sequence variations of the hypervariable region of hepatitis C virus and their clinical significance.Semantic proximity Read ↗

Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection.Semantic proximity Read ↗

Genetic alterations of the putative envelope proteins encoding region of the hepatitis C virus in the progression to relapsed phase from acute hepatitis: humoral immune response to hypervariable region 1.Semantic proximity Read ↗

Genetic characterization of hypervariable region 1 in patients chronically infected with hepatitis C virus genotype 2.Semantic proximity Read ↗

Hypervariable regions in the putative glycoprotein of hepatitis C virus.Semantic proximity Read ↗

Variations in the hypervariable region 1 of the envelope region E2 of hepatitis C virus RNA appear associated with virus persistence independently of liver disease.Semantic proximity Read ↗

Dynamics of hypervariable region 1 variation in hepatitis C virus infection and correlation with clinical and virological features of liver disease.Semantic proximity Read ↗

Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus.Semantic proximity Read ↗

Conservation of the Conformation and Positive Charges of Hepatitis C Virus E2 Envelope Glycoprotein Hypervariable Region 1 Points to a Role in Cell AttachmentSemantic proximity Read ↗

The hypervariable region of the HCV genome changes sequentially during the progression of acute HCV infection to chronic hepatitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.