Article
[Sequence diversity and variability in the putative envelope proteins including hypervariable regions of hepatitis C virus].
Nihon rinsho. Japanese journal of clinical medicine - 1 Feb 1993
Nakazawa T, Hijikata M, Kato N, Shimotohno K
Abstract excerpt
Hepatitis C virus (HCV) genomes show sequence diversities among virus isolates. In particular, the putative envelope region encoding gp35 and gp70 shows on extensive sequence diversity in the whole viral genome. We identified two hypervariable regions [HVR1 (27 amino acids) and HVR2 (7 amino acids)] in the N-terminal region of gp70 of the HCV-II genotype. In the HCV-I genotype, extensive diversity of amino acid...
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