Quasispecies of hepatitis C virus and genetic drift of the hypervariable region in chronic type C hepatitis.

doi:10.1093/infdis/172.1.261

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Quasispecies of hepatitis C virus and genetic drift of the hypervariable region in chronic type C hepatitis.

The Journal of infectious diseases - 1 Jul 1995

Kao J H, Chen P J, Lai M Y, Wang T H, Chen D S

Abstract excerpt

The sequential variations of amino acid sequences in the hypervariable region (HVR)-1 of hepatitis C virus (HCV) and changes of viremia in 2 patients with different clinicopathologic courses of chronic hepatitis C were studied. By using polymerase chain reaction amplification, cloning, and sequencing of HVR-1, genetic heterogeneity of HCV was shown. The highest annual rate of consensus amino acid variation per...

Topics

Aged
Amino Acid Sequence
Base Sequence
Consensus Sequence
DNA Primers
Female
Gene Frequency
Genetic Variation
Genotype
Hepacivirus
Hepatitis C
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Polymerase Chain Reaction

RNA, Viral

Time Factors

Source

Open in PubMed

Identifiers

PMID: 7797927
DOI: 10.1093/infdis/172.1.261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7797927-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quasispecies of hepatitis C virus and genetic drift of the hypervariable region in chronic type C hepatitis.PMID 7797927Read ↗

[Evolution of hepatitis C virus quasispecies during natural disease progression of chronic hepatitis C and the clinical implications].Semantic proximity Read ↗

Sequence variations of the hypervariable region of hepatitis C virus and their clinical significance.Semantic proximity Read ↗

Complexity of the HVR-1 quasispecies and disease activity in patients with hepatitis C.Semantic proximity Read ↗

Dynamics of hypervariable region 1 variation in hepatitis C virus infection and correlation with clinical and virological features of liver disease.Semantic proximity Read ↗

Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection.Semantic proximity Read ↗

Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity.Semantic proximity Read ↗

Characterization of hypervariable region in hepatitis C virus envelope protein during acute and chronic infection.Semantic proximity Read ↗

Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: variability and stability.Semantic proximity Read ↗

Dynamic coinfection with multiple viral subtypes in acute hepatitis C.Semantic proximity Read ↗

Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection.Semantic proximity Read ↗

Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes.Semantic proximity Read ↗

Differences in hypervariable region 1 quasispecies of hepatitis C virus between human serum and peripheral blood mononuclear cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.