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Gene polymorphism in apolipoprotein E and presenilin-1 in patients with late-onset Alzheimer's disease.

Chinese medical journal - 1 Apr 2000

Cui T, Zhou X, Jin W, Zheng F, Cao X

Abstract excerpt

OBJECTIVE: To evaluate the association of apolipoprotein E (apoE) and presenilin-1 (PS-1) gene polymorphism with late-onset Alzheimer's disease (AD). METHODS: A case-control study was undertaken to detect the polymorphism of apoE and PS-1 by polymerase chain reaction and digestion with the endonucleases of BspL I, Hha I and BamH I. RESULTS: The frequencies of apoE epsilon 3/4 genotype and epsilon 4 allele in...

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PMID: 11775232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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