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Presenilin-1 polymorphism in Alzheimer's disease and vascular dementia.

Experimental neurology - 1 Aug 1997

Matsushita S, Arai H, Muramatsu T, Makimoto K, Nakagawa T, Sasaki H, Higuchi S

Abstract excerpt

Recent reports suggest an association between an intronic polymorphism at the 3' position of exon 8 of the presenilin-1 (PS-1) gene and late-onset Alzheimer's disease (AD), but little is known about its role in the pathogenesis of AD. By genotyping 193 Japanese patients with vascular dementia or AD, and 186 elderly control subjects, we have shown no association between vascular dementia and this PS-1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9270069
DOI: 10.1006/exnr.1997.6558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Presenilin-1 polymorphism in Alzheimer's disease and vascular dementia.PMID 9270069Read ↗

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Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease.Semantic proximity Read ↗

Presenilin-1 gene intronic polymorphism in sporadic and familial Alzheimer's disease.Semantic proximity Read ↗

Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Alzheimer's Disease Collaborative Group.Semantic proximity Read ↗

Case-control study of presenilin-1 intronic polymorphism in sporadic early and late onset Alzheimer's disease.Semantic proximity Read ↗

Presenilin-1 gene intronic polymorphism and late-onset Alzheimer's disease.Semantic proximity Read ↗

No association between the intronic presenilin 1 polymorphism and Alzheimer's disease in the Chinese population.Semantic proximity Read ↗

Apolipoprotein E and intronic polymorphism of presenilin 1 and alpha-1-antichymotrypsin in Alzheimer's disease and vascular dementia.Semantic proximity Read ↗

No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer's disease.Semantic proximity Read ↗

Presenilin gene predisposes to late-onset degenerative but not vascular dementia: a comparative study of PS1 and ApoE genes in a North Indian Cohort.Semantic proximity Read ↗

Association of apolipoprotein E genotype and intronic polymorphism of the presenilin-1 gene with Alzheimer's disease in elderly Taiwan Chinese.Semantic proximity Read ↗

Association study and meta-analysis of Alzheimer's disease risk and presenilin-1 intronic polymorphism.Semantic proximity Read ↗

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