Association of apolipoprotein E genotype and intronic polymorphism of the presenilin-1 gene with Alzheimer's disease in elderly Taiwan Chinese.

doi:10.1016/s0022-510x(98)00052-5

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Article

Association of apolipoprotein E genotype and intronic polymorphism of the presenilin-1 gene with Alzheimer's disease in elderly Taiwan Chinese.

Journal of the neurological sciences - 7 May 1998

Hu C J, Sung S M, Liu H C, Chang J G

Abstract excerpt

We studied the apoliprotein E (apo-E) allele frequencies and intronic polymorphism of the presenilin-1 (PS-1) gene in 55 patients with late-onset Alzheimer's disease (AD) and 93 age- and sex-matched controls. The apoE epsilon4 allele frequency was significantly higher in the AD group than in the...

Topics

Aged
Alzheimer Disease
Apolipoproteins E
Asian People
Female
Genotype
Humans
Introns
Male
Membrane Proteins
Polymerase Chain Reaction
Polymorphism, Genetic
Presenilin-1
Taiwan

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