Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Case-control study of presenilin-1 intronic polymorphism in sporadic early and late onset Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Jun 1999

Yasuda M, Hirono N, Maeda K, Imamura T, Mori E, Tanaka C

Abstract excerpt

OBJECTIVE: Presenilin-1 is a major causative gene for early onset familial Alzheimer's disease, and the apolipoprotein E epsilon4 allele is a major genetic risk factor known to influence late onset and sporadic early onset Alzheimer's disease. The presenilin-1 1/1 genotype has recently been reported to be associated with sporadic Alzheimer's disease. The purpose of this study is to determine whether Alzheimer's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Case-Control Studies

Share to Membrane Proteins

Share to Presenilin-1

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 10329743
DOI: 10.1136/jnnp.66.6.722
PMCID: PMC1736406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Case-control study of presenilin-1 intronic polymorphism in sporadic early and late onset Alzheimer's disease.PMID 10329743Read ↗

Presenilin-1 gene intronic polymorphism and late-onset Alzheimer's disease.Semantic proximity Read ↗

Association of apolipoprotein E genotype and intronic polymorphism of the presenilin-1 gene with Alzheimer's disease in elderly Taiwan Chinese.Semantic proximity Read ↗

Association study and meta-analysis of Alzheimer's disease risk and presenilin-1 intronic polymorphism.Semantic proximity Read ↗

Gene polymorphism in apolipoprotein E and presenilin-1 in patients with late-onset Alzheimer's disease.Semantic proximity Read ↗

Polymorphism of the regulatory region of the presenilin-2 gene in sporadic Alzheimer's disease: a case-control study.Semantic proximity Read ↗

Association between presenilin 1 intronic polymorphism and late onset Alzheimer's disease in the North Chinese population.Semantic proximity Read ↗

Presenilin-1 polymorphism in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia in Japanese population.Semantic proximity Read ↗

Presenilin-1 polymorphism in Alzheimer's disease and vascular dementia.Semantic proximity Read ↗

Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Alzheimer's Disease Collaborative Group.Semantic proximity Read ↗

An intronic rare mutation in Presenilin-1 (PSEN-1) gene may be involved in the developement of Alzheimer’s diseaseSemantic proximity Read ↗

Presenilin 1 polymorphism associated with Alzheimer's disease in apolipoprotein E4 carriers.Semantic proximity Read ↗

Presenilin 1 intronic polymorphism is not associated with Alzheimer type neuropathological changes or sporadic Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.