Article
NADH/NADPH oxidase p22 phox gene polymorphism is associated with improved coronary endothelial vasodilator function.
European heart journal - 1 Jan 2001
Schächinger V, Britten M B, Dimmeler S, Zeiher A M
Abstract excerpt
AIMS: The NADH/NADPH oxidase system plays a central role in vascular superoxide anion production, which appears to cause coronary endothelial dysfunction. Recently, it has been suggested that the C242T polymorphism of the NADH/NADPH oxidase p22 phox gene can reduce susceptibility to coronary artery disease. We therefore tested whether this polymorphism is associated with an altered endothelium-dependent...
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