Article
NAD(P)H oxidase p22phox Gene C242T polymorphism and lipoprotein oxidation.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2003
Nakano Takanari, Matsunaga Seiko, Nagata Atsuo, Maruyama Taro
Abstract excerpt
BACKGROUND: Vascular NAD(P)H oxidase is a key enzyme of superoxide anion production in human vessel walls. The C242T mutation in the CYBA gene coding for p22phox, a component of the enzyme, may change the redox state. The aim of this study was to evaluate the influence of the polymorphism on serum concentrations of oxidative stress markers. METHODS: Serum samples were collected from 134 Type 2 diabetic patients...
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