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Article

Kv beta subunit oxidoreductase activity and Kv1 potassium channel trafficking.

The Journal of biological chemistry - 8 Mar 2002

Campomanes Claire R, Carroll Karen I, Manganas Louis N, Hershberger Marcia E, Gong Belvin, Antonucci Dana E, Rhodes Kenneth J, Trimmer James S

Abstract excerpt

Voltage-gated Kv1 potassium channels consist of pore-forming alpha subunits and cytoplasmic Kv beta subunits. The latter play diverse roles in modulating the gating, stability, and trafficking of Kv1 channels. The crystallographic structure of the Kv beta2 subunit revealed surprising structural homology with aldo-keto reductases, including a triosephosphate isomerase barrel structure, conservation of key...

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Identifiers

PMID: 11748234
DOI: 10.1074/jbc.M110276200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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