Article
Kvbeta subunits increase expression of Kv4.3 channels by interacting with their C termini.
The Journal of biological chemistry - 16 Feb 2001
Yang E K, Alvira M R, Levitan E S, Takimoto K
Abstract excerpt
Auxiliary Kvbeta subunits form complexes with Kv1 family voltage-gated K(+) channels by binding to a part of the N terminus of channel polypeptide. This association influences expression and gating of these channels. Here we show that Kv4.3 proteins are associated with Kvbeta2 subunits in the brain. Expression of Kvbeta1 or Kvbeta2 subunits does not affect Kv4.3 channel gating but increases current density and...
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