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Article

Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression.

Proceedings of the National Academy of Sciences of the United States of America - 11 Dec 2007

Yang Jae-Won, Vacher Helene, Park Kang-Sik, Clark Eliana, Trimmer James S

Abstract excerpt

Kv1.2 alpha-subunits are components of low-threshold, rapidly activating voltage-gated potassium (Kv) channels in mammalian neurons. Expression and localization of Kv channels is regulated by trafficking signals encoded in their primary structure. Kv1.2 is unique in lacking strong trafficking signals and in exhibiting dramatic cell-specific differences in trafficking, which is suggestive of conditional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18056633
DOI: 10.1073/pnas.0708574104
PMCID: PMC2148421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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