Article
A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels.
The Journal of biological chemistry - 19 Sept 2003
Shibata Riichi, Misonou Hiroaki, Campomanes Claire R, Anderson Anne E, Schrader Laura A, Doliveira Lisa C, Carroll Karen I, Sweatt J David, Rhodes Kenneth J, Trimmer James S
Abstract excerpt
Kv4 potassium channels regulate action potentials in neurons and cardiac myocytes. Co-expression of EF hand-containing Ca2+-binding proteins termed KChIPs with pore-forming Kv4 alpha subunits causes changes in the gating and amplitude of Kv4 currents (An, W. F., Bowlby, M. R., Betty, M., Cao, J., Ling, H. P., Mendoza, G., Hinson, J. W., Mattsson, K. I., Strassle, B. W., Trimmer, J. S., and Rhodes, K. J. (2000)...
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