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Article

Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2001

Schubert F R, Tremblay P, Mansouri A, Faisst A M, Kammandel B, Lumsden A, Gruss P, Dietrich S

Abstract excerpt

The paired box containing transcription factor Pax3 is a crucial regulator of dermomyotome and muscle development. However, the allelic series of Pax3/Splotch mutants also displays characteristic vertebral column malformations, which do not result from defective dorsoventral somite pattern. Rather, vertebral column and sclerotomal phenotypes are reminiscent of the phenotypes observed in the...

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PMID: 11747084
DOI: 10.1002/dvdy.1211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites.PMID 11747084Read ↗

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