Article
Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis.
Current biology : CB - 16 Sept 2003
Barrios Arantza, Poole Richard J, Durbin Lindsey, Brennan Caroline, Holder Nigel, Wilson Stephen W
Abstract excerpt
BACKGROUND: During somitogenesis, segmental patterns of gene activity provide the instructions by which mesenchymal cells epithelialize and form somites. Various members of the Eph family of transmembrane receptor tyrosine kinases and their Ephrin ligands are expressed in a segmental pattern in the rostral presomitic mesoderm. This pattern establishes a receptor/ligand interface at each site of somite furrow...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
