Article
A crucial role for Pax3 in the development of the hypaxial musculature and the long-range migration of muscle precursors.
Developmental biology - 1 Nov 1998
Tremblay P, Dietrich S, Mericskay M, Schubert F R, Li Z, Paulin D
Abstract excerpt
Activated by dorsalizing and lateralizing signals, the Pax3 gene is an early marker for the entire paraxial mesoderm and its dorsal derivative, the dermomyotome. Later, its expression becomes restricted to the lateral dermomyotome and to the migratory muscle precursors giving rise to the hypaxial musculature. To understand better the role that Pax3 plays during development of paraxial mesoderm-derived structures,...
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