Article
Pax genes and neural tube defects in the mouse.
Ciba Foundation symposium - 1 Jan 1994
Goulding M, Paquette A
Abstract excerpt
The Pax genes encode a family of transcription factors that are expressed in restricted regions of the developing embryo. Several Pax genes are expressed in the developing nervous system where they are believed to regulate the morphogenesis of neural structures. Loss-of-function mutations in the Pax-3 gene have been identified in a number of alleles of the mouse mutant splotch. In homozygous splotch embryos...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.