Article
Pax genes and neural tube defects in the mouse.
Ciba Foundation symposium - 1 Jan 1994
Goulding M, Paquette A
Abstract excerpt
The Pax genes encode a family of transcription factors that are expressed in restricted regions of the developing embryo. Several Pax genes are expressed in the developing nervous system where they are believed to regulate the morphogenesis of neural structures. Loss-of-function mutations in the...
Topics
- Animals
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Gene Expression
- Genes, Homeobox
- Mice
- Mutation
- Nervous System
- Neural Tube Defects
- Phenotype
- Waardenburg Syndrome