Article
Genetic identification of multiple susceptibility genes involved in the development of endometrial carcinoma in a rat model.
International journal of cancer - 15 Dec 2001
Roshani L, Wedekind D, Szpirer J, Taib Z, Szpirer C, Beckmann B, Rivière M, Hedrich H J, Klinga-Levan K
Abstract excerpt
There are clear indications that inheritance plays an essential role in certain cases of human endometrial cancer, and there are at least 2 forms of early-onset heritable endometrial adenocarcinomas (EACs). Females of the BDII inbred rat strain are known to be genetically predisposed to endometrial carcinoma, and we have performed a genetic analysis of susceptibility to endometrial cancer in this strain. F(2)...
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