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Article

Molecular classification of spontaneous endometrial adenocarcinomas in BDII rats.

Endocrine-related cancer - 1 Mar 2009

Samuelson Emma, Hedberg Carola, Nilsson Staffan, Behboudi Afrouz

Abstract excerpt

Female rats of the BDII/Han inbred strain are prone to spontaneously develop endometrial carcinomas (EC) that in cell biology and pathogenesis are very similar to those of human. Human EC are classified into two major groups: Type I displays endometroid histology, is hormone-dependent, and characterized by frequent microsatellite instability and PTEN, K-RAS, and CTNNB1 (beta-Catenin) mutations; Type II shows...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19075038
DOI: 10.1677/ERC-08-0185

Genes

CDH1
CTNNB1
ERBB2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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