Article
Recurrent chromosome 10 aberrations and Tp53 mutations in rat endometrial adenocarcinomas.
Advances in experimental medicine and biology - 1 Jan 2008
Nordlander Carola, Samuelson Emma, Klinga-Levan Karin, Behboudi Afrouz
Abstract excerpt
Human genetic heterogeneity and differences in the environment and life style make analysis of complex diseases such as cancer difficult. By using inbred animal strains, the genetic variability can be minimized and the environmental factors can be reasonably controlled. Endometrial adenocarcinoma (EAC) is the most common gynecologic malignancy, ranking fourth in incidence among tumors in women. The inbred BDII...
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