Article
Genetic mapping of mammary tumor traits to rat chromosome 10 using a novel panel of consomic rats.
Cancer genetics and cytogenetics - 1 Oct 2008
Adamovic Tatjana, McAllister Donna, Rowe J Jordi, Wang Tao, Jacob Howard J, Sugg Sonia L
Abstract excerpt
Identification of novel breast cancer susceptibility and resistance genes in genetically diverse human populations is challenging, and so inbred rats have been used to identify novel mammary cancer susceptibility quantitative trait loci (QTLs) with conventional mapping approaches. An alternative approach for QTL mapping is to use chromosome substitution (consomic) rat strains, which has the advantage of rapid...
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