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Article

Independent amplification of two gene clusters on chromosome 4 in rat endometrial cancer: identification and molecular characterization.

Cancer research - 15 Nov 2001

Walentinsson A, Helou K, Wallenius V, Hedrich H J, Szpirer C, Levan G

Abstract excerpt

The BDII rat is genetically predisposed to hormone-dependent endometrial adenocarcinoma and was used to model human cancer. Tumors arising spontaneously in strain crosses involving BDII rats were analyzed by means of comparative genome hybridization. The most common aberration was amplification of the proximal region of rat chromosome 4, centered around bands q12-q22. The copy numbers of 15 cancer-related genes...

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PMID: 11719459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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