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Article

Molecular disorders in transitional vs. peripheral zone prostate adenocarcinoma.

International journal of cancer - 1 Nov 2001

Colombo P, Patriarca C, Alfano R M, Cassani B, Ceva Grimaldi G, Roncalli M, Bosari S, Coggi G, Campo B, Gould V E

Abstract excerpt

Loss of heterozygosity (LOH) and microsatellite instability (MSI) have been shown to be mechanisms for tumor-suppressor gene inactivation in human oncogenesis. In our study, we examined LOH and MSI using 16 polymorphic markers of DNA for chromosomes 1, 3, 7, 8, 10 and 11. Microdissected tumor samples were isolated from 32 patients, representing 11 foci of incidentally discovered prostate cancer of the...

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Identifiers

PMID: 11745418
DOI: 10.1002/ijc.1485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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