Article
Allelic imbalance and microsatellite instability in prostatic adenocarcinoma.
Cancer research - 1 Oct 1996
Cunningham J M, Shan A, Wick M J, McDonnell S K, Schaid D J, Tester D J, Qian J, Takahashi S, Jenkins R B, Bostwick D G, Thibodeau S N
Abstract excerpt
Although prostate cancer is one of the most common malignancies of males in Western countries, relatively little is known about the molecular mechanisms involved in tumor initiation and progression. Allelic loss studies have suggested the involvement of multiple tumor suppressor genes (TSGs), but few detailed studies of all chromosomes have been performed. In an effort to localize and identify candidate TSGs, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.