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Article

Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer.

Cancer research - 1 Sept 1993

Bova G S, Carter B S, Bussemakers M J, Emi M, Fujiwara Y, Kyprianou N, Jacobs S C, Robinson J C, Epstein J I, Walsh P C

Abstract excerpt

Allelic loss studies have been instrumental in identifying tumor suppressor gene loci in a variety of cancers. In this study we analyzed prostate cancer specimens from 52 patients for allelic loss using 8 polymorphic probes for the short arm of chromosome 8. Overall, 32 of 51 (63%) informative tumors showed loss of at least one locus on chromosome 8p. The most frequently deleted region is observed at chromosome...

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PMID: 7689419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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