Article
Schizophrenia, the prefrontal cortex, and a mechanism of genetic susceptibility.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Aug 2002
Weinberger D R
Abstract excerpt
Information-processing in the prefrontal cortex is abnormal in patients with schizophrenia. From functional neuroimaging and other studies, it appears that neurons of the dorsolateral prefrontal cortex are effectors of core clinical and biological phenomena associated with the illness. Cognitive deficits qualitatively similar to those in patients with schizophrenia are also found in their healthy siblings and...
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