Article
Equal sensitivity to cocaine reward in addiction-prone and addiction-resistant rat genotypes.
Behavioural pharmacology - 1 Nov 2001
Ranaldi R, Bauco P, McCormick S, Cools A R, Wise R A
Abstract excerpt
Rat genotypes tentatively identified as addiction-prone or addiction-resistant on the basis of alcohol preference and locomotor responsiveness to novelty--Lewis versus Fischer strains and Nijmegen high versus low responder lines--differed in time to develop intravenous cocaine self-administration habits, but did not differ in sensitivity to the ability of cocaine reward to summate with lateral hypothalamic brain...
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