Article
Assessment of the aversive and rewarding effects of alcohol in Fischer and Lewis rats.
Psychopharmacology - 1 Dec 2006
Roma Peter G, Flint Wesley W, Higley J Dee, Riley Anthony L
Abstract excerpt
RATIONALE: Application of the Fischer-Lewis genetic model of drug abuse to the study of alcohol's motivational properties has been limited. OBJECTIVES: To assess the aversive and rewarding effects of ethanol in Fischer and Lewis rats. MATERIALS AND METHODS: Fischer and Lewis rats underwent a four-trial combined conditioned taste aversion/conditioned place preference procedure (CTA/CPP; 0, 1, 1.25, or 1.5 g/kg IP...
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