Assessment of the aversive and rewarding effects of alcohol in Fischer and Lewis rats.

doi:10.1007/s00213-006-0553-6

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Article

Assessment of the aversive and rewarding effects of alcohol in Fischer and Lewis rats.

Psychopharmacology - 1 Dec 2006

Roma Peter G, Flint Wesley W, Higley J Dee, Riley Anthony L

Abstract excerpt

RATIONALE: Application of the Fischer-Lewis genetic model of drug abuse to the study of alcohol's motivational properties has been limited. OBJECTIVES: To assess the aversive and rewarding effects of ethanol in Fischer and Lewis rats. MATERIALS AND METHODS: Fischer and Lewis rats underwent a four-trial combined conditioned taste aversion/conditioned place preference procedure (CTA/CPP; 0, 1, 1.25, or 1.5 g/kg IP...

Topics

Alcohol Drinking
Animals
Avoidance Learning
Behavior, Animal
Body Temperature
Central Nervous System Depressants
Conditioning, Psychological
Dose-Response Relationship, Drug
Ethanol
Genotype
Male
Rats
Rats, Inbred F344
Rats, Inbred Lew
Saccharin
Substance-Related Disorders
Taste

Source

Open in PubMed

Identifiers

PMID: 17013639
DOI: 10.1007/s00213-006-0553-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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