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Article

Alcohol-preferring (P) rats are more sensitive than Wistar rats to the reinforcing effects of cocaine self-administered directly into the nucleus accumbens shell.

Pharmacology, biochemistry, and behavior - 1 Oct 2011

Katner Simon N, Oster Scott M, Ding Zheng-Ming, Deehan Gerald A, Toalston Jamie E, Hauser Sheketha R, McBride William J, Rodd Zachary A

Abstract excerpt

Wistar rats will self-administer cocaine directly into the nucleus accumbens shell (AcbSh), but not into the nucleus accumbens core. In human and animal literature, there is a genetic association between alcoholism and cocaine dependency. The current experiment examined whether selective breeding for high alcohol preference is also associated with greater sensitivity of the AcbSh to the reinforcing properties of...

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Source

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Identifiers

PMID: 21723879
DOI: 10.1016/j.pbb.2011.06.021
PMCID: PMC3156309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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