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Article

Genetic determinants of susceptibility to the rewarding and other behavioral actions of cocaine.

Journal of addictive diseases - 1 Jan 1991

Seale T W, Carney J M

Abstract excerpt

The role of genotype as a determinant of biologically based inter-individual differences in vulnerability to substance abuse has received little systematic investigation except in the case of alcohol. This report describes the use of an animal model, the inbred mouse, to identify and to characterize variants with inherently altered susceptibilities to the rewarding and other behavioral actions of cocaine. Among a...

Topics

Animals
Appetitive Behavior
Arousal
Brain
Cocaine
Genotype
Mice
Mice, Inbred Strains
Models, Genetic
Polymorphism, Genetic
Reward
Social Environment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Species Specificity

Substance-Related Disorders

Source

Identifiers

PMID: 2065114
DOI: 10.1300/J069v10n01_10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2065114-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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