Article
A rapid screening method for a single nucleotide polymorphism (SNP) in the human MOR gene.
British journal of clinical pharmacology - 1 Dec 2001
Grösch S, Niederberger E, Lötsch J, Skarke C, Geisslinger G
Abstract excerpt
AIMS: Genetic association studies have suggested that the single nucleotide polymorphism (SNP) at position 118 of the human mu-opioid receptor (MOR) gene could be a potential risk factor for drug treatment variability in patients. Therefore, we wanted to develop a fast and reliable detection method for this SNP which is applicable in a clinical setting. METHODS: To detect the polymorphism at position A118-->G in...
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