Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Consequences of the 118A&gt;G polymorphism in the OPRM1 gene: translation from bench to bedside?

1 May 2013

Abstract excerpt

The 118A>G single nucleotide polymorphism (SNP) in the μ-opioid receptor (OPRM1) gene has been the most described variant in pharmacogenetic studies regarding opioid drugs. Despite evidence for an altered biological function encoded by this variant, this knowledge is not yet utilized clinically. The aim of the present review was to collect and discuss the available information on the 118A>G SNP in the OPRM1 gene,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pain Management and Opioid Use
Share to Pharmacological Receptor Mechanisms and Effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23658496
DOI: 10.2147/jpr.s42040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Consequences of the 118A&gt;G polymorphism in the OPRM1 gene: translation from bench to bedside?PMID 23658496Read ↗

µ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain.Semantic proximity Read ↗

The OPRM1 A118G Polymorphism Revisited: Recent Developments and Implications for Personalized Treatment.Semantic proximity Read ↗

The μ-opioid receptor gene polymorphism 118A>G weakens the pharmacological action of buprenorphine.Semantic proximity Read ↗

Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment.Semantic proximity Read ↗

Overview of genetic analysis of human opioid receptors.Semantic proximity Read ↗

Overview of Genetic Analysis of Human Opioid Receptors.Semantic proximity Read ↗

Functional differences in the mu opioid receptor SNP 118A>G are dependent on receptor splice-variant and agonist-specific recruitment of β-arrestin.Semantic proximity Read ↗

Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population.Semantic proximity Read ↗

No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.Semantic proximity Read ↗

Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers.Semantic proximity Read ↗

[Genetic polymorphism affects the clinical effects of opioids after surgery].Semantic proximity Read ↗

Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.