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Article

The G allele of SNP E1/A118G at the mu-opioid receptor gene locus shows genomic evidence of recent positive selection.

Pharmacogenomics - 1 Jul 2009

Pang Grace S Y, Wang Jingbo, Wang Zihua, Goh Cynthia, Lee Caroline G L

Abstract excerpt

Opioid drug response and pain perception differs greatly amongst different individuals. The micro-opioid receptor (MOR) is the main receptor target for important opioid analgesics. As SNPs may contribute to interindividual differences in drug response, in silico signatures of recent positive selection (RPS) were utilized to seek out potentially functional SNPs in the MOR gene in order to facilitate the...

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PMID: 19604083
DOI: 10.2217/pgs.09.63

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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