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Article

p73 is over-expressed in vulval cancer principally as the Delta 2 isoform.

British journal of cancer - 16 Nov 2001

O'Nions J, Brooks L A, Sullivan A, Bell A, Dunne B, Rozycka M, Reddy A, Tidy J A, Evans D, Farrell P J, Evans A, Gasco M, Gusterson B, Crook T

Abstract excerpt

p73 was studied in squamous cancers and precursor lesions of the vulva. Over-expression of p73 occurred commonly in both human papillomavirus (HPV)-positive and -negative squamous cell cancers (SCC) and high-grade premalignant lesions. Whereas expression in normal vulval epithelium was detected only in the basal and supra-basal layers, expression in neoplastic epithelium increased with grade of neoplasia, being...

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Share to Neoplasms, Squamous Cell
Share to Oncogene Proteins, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Papillomavirus E7 Proteins

Share to RNA, Neoplasm

Share to Tumor Protein p73

Share to Tumor Suppressor Protein p14ARF

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Source

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Identifiers

PMID: 11720444
DOI: 10.1054/bjoc.2001.2138
PMCID: PMC2363945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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