Article

The E2F4/p130 repressor complex cooperates with oncogenic ΔNp73α to promote cell survival in human papillomavirus 38 E6/E7-transformed keratinocytes and in cancer cells

2022-10-30

Abstract excerpt

<h4>ABSTRACT</h4> Tumor suppressor p53 and its related proteins, p63 and p73, can be synthesized as multiple isoforms lacking part of the N- or C-terminal regions. Specifically, high expression of the ΔNp73α isoform is notoriously associated with various human malignancies characterized by poor prognosis. This isoform is also accumulated by oncogenic viruses such as Epstein–Barr virus (EBV), as well as genus beta...

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Literature Corpus work: 35b7bab7-5100-5ca8-8660-c6f8ecf36952
DOI: 10.1101/2022.10.27.514150

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