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Article

Squamous Precursor Lesions of the Vulva: A Practical Approach.

Dermatologic clinics - 1 Apr 2026

Crimmins Jennifer, Schneider Michelle M, Selim M Angelica

Abstract excerpt

Vulvar squamous cell carcinoma and its precursors are heterogeneous and classified into 3 biologically distinct subgroups: human papillomavirus (HPV)-associated, HPV-independent TP53-mutated, and HPV-independent TP53-wild type. Although nomenclature is established for HPV-associated high-grade squamous intraepithelial lesion and TP53-mutated differentiated vulvar intraepithelial neoplasia lesions, terminology for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41951322
DOI: 10.1016/j.det.2026.01.015

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

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