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Article

Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome.

Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2006

Winkelmann Juliane, Lichtner Peter, Pütz Benno, Trenkwalder Claudia, Hauk Stephanie, Meitinger Thomas, Strom Tim, Muller-Myhsok Bertram

Abstract excerpt

Restless legs syndrome (RLS; MIM 102300) is a common neurological disorder characterized by dysesthesias and an urge to move the lower limbs. The symptoms predominantly occur at rest, in the evening, and improve with movement. There is a high familial aggregation but gene mutations have not yet been found. Three loci for RLS on chromosomes 12q, 14q, and 9p (RLS-1, RLS-2, and RLS-3) have been reported with a...

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Identifiers

PMID: 16124010
DOI: 10.1002/mds.20627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome.PMID 16124010Read ↗

Family-based association study of the restless legs syndrome loci 2 and 3 in a European population.Semantic proximity Read ↗

[Advances in genetics of restless legs syndrome].Semantic proximity Read ↗

A novel locus for restless legs syndrome on chromosome 13q.Semantic proximity Read ↗

Evidence for linkage of restless legs syndrome to chromosome 9p: are there two distinct loci?Semantic proximity Read ↗

Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13.Semantic proximity Read ↗

Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q.Semantic proximity Read ↗

Restless legs syndrome: an update on genetics and future perspectives.Semantic proximity Read ↗

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.Semantic proximity Read ↗

Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity.Semantic proximity Read ↗

Autosomal dominant restless legs syndrome maps on chromosome 14q.Semantic proximity Read ↗

Genomewide linkage scan identifies a novel susceptibility locus for restless legs syndrome on chromosome 9p.Semantic proximity Read ↗

A novel locus for restless legs syndrome maps to chromosome 19p in an Irish pedigree.Semantic proximity Read ↗

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