Article
Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity.
Archives of neurology - 1 Apr 2005
Desautels Alex, Turecki Gustavo, Montplaisir Jacques, Xiong Lan, Walters Arthur S, Ehrenberg Bruce L, Brisebois Kateri, Desautels Amelie K, Gingras Yves, Johnson William G, Lugaresi Elio, Coccagna Giorgio, Picchietti Daniel L, Lazzarini Alice, Rouleau Guy A
Abstract excerpt
BACKGROUND: Genes are involved in the etiology of restless legs syndrome, a common sensorimotor disorder. OBJECTIVES: To replicate and to further characterize our previously reported chromosome 12q linkage results. DESIGN: Family linkage study. SETTING AND PARTICIPANTS: A total of 276 individuals from 19 families have been examined using a selection of markers spanning the identified candidate interval on...
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