Article
Neuralized functions as an E3 ubiquitin ligase during Drosophila development.
Current biology : CB - 30 Oct 2001
Yeh E, Dermer M, Commisso C, Zhou L, McGlade C J, Boulianne G L
Abstract excerpt
The Notch pathway is a widely studied means of intercellular signaling responsible for the determination of cell fate, cell differentiation, and boundary formation (reviewed in ). The main effectors of this pathway, Notch (N) and Delta (Dl), have been shown to function as a receptor and ligand, respectively. Genetic and phenotypic studies suggest that Neuralized (Neu), a RING finger protein, also plays a role...
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