Article
Protection by dietary compounds against mutation in a transgenic rodent.
The Journal of nutrition - 1 Nov 2001
de Boer J G
Abstract excerpt
One of the most relevant biomarkers of genotoxicity and, potentially, carcinogenesis is the occurrence of mutations. Data indicate that carcinogens are highly specific with regard to their target tissue in inducing both tumors and mutations. This specificity may reflect the dependence on tissue-specific metabolic activation, the organ-specific environment or both. Ideally, therefore, mutation should be determined...
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