Transgenic assays for mutations and cancer: current status and future perspectives.

doi:10.1016/s0027-5107(98)00030-x

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Article

Transgenic assays for mutations and cancer: current status and future perspectives.

Mutation research - 25 May 1998

Vijg J, van Steeg H

Abstract excerpt

Transgenic mouse modelling has proved to be a powerful approach to explore the various steps involved in spontaneous and induced carcinogenesis. Some of the multitude of models currently available have the potential to become a substitute for the expensive, long-term rodent bioassay to predict ca...

Topics

Animals
Biological Assay
Carcinogenicity Tests
Disease Models, Animal
Mice
Mice, Transgenic
Mutation
Neoplasms, Experimental

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