Article
Transgenic assays for mutations and cancer: current status and future perspectives.
Mutation research - 25 May 1998
Vijg J, van Steeg H
Abstract excerpt
Transgenic mouse modelling has proved to be a powerful approach to explore the various steps involved in spontaneous and induced carcinogenesis. Some of the multitude of models currently available have the potential to become a substitute for the expensive, long-term rodent bioassay to predict carcinogenicity of environmental compounds. Here, we review the progress in the development and use of transgenic mouse...
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