Article
Antimutagenicity of green tea polyphenols in the liver of transgenic medaka.
Environmental and molecular mutagenesis - 1 Aug 2005
Winn Richard N, Kling Heather, Norris Michelle B
Abstract excerpt
We examined the ability of a mixture of the predominant green tea polyphenolic compounds (GTP) to reduce benzo[a]pyrene (B[a]P)-induced mutations in the cII gene of the lambda transgenic medaka. Fish were treated with 50 ppb B[a]P for 24 hr, followed by exposure to 2 ppm or 10 ppm GTP for 28 days. cII mutations in livers of fish exposed to B[a]P were increased significantly, 2.6-fold above controls. In contrast,...
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