Aldosterone synthase (CYP11B2) polymorphisms and cardiovascular function.

doi:10.3109/07435809809032690

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Article

Aldosterone synthase (CYP11B2) polymorphisms and cardiovascular function.

Endocrine research - 1 Jan 2000

White P C, Hautanen A, Kupari M

Abstract excerpt

In addition to regulating renal sodium resorption and, thus, intravascular volume, aldosterone may have direct effects on the cardiovascular system. We previously identified a polymorphism (-344C/T) in the promoter of the aldosterone synthase (CYP11B2) gene that affects binding of the SF-1 transc...

Topics

Adult
Aldosterone
Alleles
Baroreflex
Blood Pressure
Cardiovascular Physiological Phenomena
Coronary Disease
Cytochrome P-450 CYP11B2
Echocardiography
Female
Genetic Predisposition to Disease
Humans
Hypertrophy, Left Ventricular
Male
Polymorphism, Genetic
Reference Values
Smoking
Ventricular Function, Left

Source

Open in PubMed

Identifiers

PMID: 9888580
DOI: 10.3109/07435809809032690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9888580-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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