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Article

Aldosterone synthase (CYP11B2) polymorphisms and cardiovascular function.

The Journal of steroid biochemistry and molecular biology - 1 Jan 2000

White P C, Hautanen A, Kupari M

Abstract excerpt

In addition to regulating renal sodium resorption and, thus, intravascular volume, aldosterone may have direct effects on the cardiovascular system. We previously identified a polymorphism (-344C/T) in the promoter of the aldosterone synthase (CYP11B2) gene that affects binding of the SF-1 transc...

Topics

Alleles
Baroreflex
Cardiomegaly
Cardiovascular Physiological Phenomena
Cytochrome P-450 CYP11B2
Humans
Organ Size
Polymorphism, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10419019
DOI: 10.1016/s0960-0760(99)00071-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10419019-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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