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Article

Catechol-O-methyltransferase (COMT) genetic polymorphism in a Turkish population.

Archives of toxicology - 1 Sept 2001

Kocabaş N A, Karakaya A E, Cholerton S, Sardaş S

Abstract excerpt

Catechol-O-methyltransferase (COMT) inactivates neurotransmitters, catechol hormones and drugs such as levodopa and methyldopa. A low activity allele has been demonstrated at codon 108/158 of the soluble and membrane-bound COMT, respectively, whereby a G to A transition results in a valine to methionine substitution. Ethnic and inter-individual differences in red blood cell COMT activity have been observed in the...

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Source

Identifiers

PMID: 11693181
DOI: 10.1007/s002040100252

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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