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Article

Catechol-O-methyltransferase and Parkinson's disease.

Acta medica Okayama - 1 Feb 2002

Tai Chun-Hwi, Wu Ruey-Meei

Abstract excerpt

Parkinson's disease (PD) is one of the main causes of neurological disability in the elderly. Levodopa is the gold standard for treating this disease, but chronic levodopa therapy is complicated by motor fluctuation and dyskinesia. The catechol-O-methyltransferase (COMT) inhibitors represent a new class of antiparkinsonian drugs. When coadministered with levodopa/decarboxylase inhibitor, 2 COMT inhibitors,...

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Source

Identifiers

PMID: 11873938
DOI: 10.18926/AMO/31725

Genes

COMT
MAOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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